Question 1

Who makes acetaminophen + caffeine?

Accepted Answer

Acetaminophen + Caffeine is a fixed-dose combination of Acetaminophen and Caffeine. There is no combination-level drug master file; it is sourced as a finished combination or built from its component APIs. Its component-API makers are listed below; each holds its own regulatory filing.

Question 2

Where do the APIs in acetaminophen + caffeine come from?

Accepted Answer

Acetaminophen: 20 verified API manufacturers. Caffeine: 11 verified API manufacturers. Each links to its own ranked supplier page.

Question 3

What strengths does acetaminophen + caffeine come in?

Accepted Answer

Common marketed ratios include 500/500, 356/30, 65/500, 713/60, 325/30 (mg per component). Ratios come from the finished-product records as at 29 July 2026.

Acetaminophen + Caffeine FDC suppliers and manufacturers

Component APIs — where each ingredient comes from

Acetaminophen API manufacturers

Caffeine API manufacturers

Source this combination

Component molecule pages