Molecules / Codeine

Codeine API manufacturers

CAS 76-57-3 ATC R05DA04 Updated 9 July 2026
28
manufacturers with an active filing 9 of them hold a US DMF or a CEP
109
shortage records on file across 8 countries
651
finished-dose makers across 38 regulators
Showing 20 of 28 manufacturers This list is ranked on evidence. Placement cannot be purchased.

Ranked API manufacturers

01

Specgx

United States
Makes the API
Credentials confirmed against the regulator files on 25 July 2026

Holds 2 active US DMFs and one valid CEP for codeine, filing since 1983. Its 2025 FDA inspection closed as VAI, and its GMP is recognised in 2 markets.

US DMF
2 active
CEP
1 valid
Last FDA inspection
2025 · VAI
GMP recognised in
2 markets
02

Siegfried USA

United States
Makes the API
Credentials confirmed against the regulator files on 25 July 2026

Holds one active US DMF for codeine, filing since 2007. Its 2025 FDA inspection closed as NAI.

US DMF
1 active
CEP
None on file
Last FDA inspection
2025 · NAI
GMP recognised in
Not established
How this listing is sourced FDA, List of Drug Master Files
View profile
03

Chattem Chemicals

United States
Makes the API
Credentials confirmed against the regulator files on 25 July 2026

Holds one active US DMF for codeine, filing since 2022. Its 2022 FDA inspection closed as NAI.

US DMF
1 active
CEP
None on file
Last FDA inspection
2022 · NAI
GMP recognised in
Not established
How this listing is sourced FDA, List of Drug Master Files
View profile
04

Macfarlan Smith

United Kingdom
Makes the API
Credentials confirmed against the regulator files on 25 July 2026

Holds 2 valid CEPs for codeine, filing since 2014. Its 2021 FDA inspection closed as VAI, and its GMP is recognised in 1 market.

US DMF
None on file
CEP
2 valid
Last FDA inspection
2021 · VAI
GMP recognised in
1 markets
05

Noramco

United States
Makes the API
Credentials confirmed against the regulator files on 25 July 2026

Holds one active US DMF for codeine, filing since 2012. Its 2025 FDA inspection closed as VAI.

US DMF
1 active
CEP
None on file
Last FDA inspection
2025 · VAI
GMP recognised in
Not established
How this listing is sourced FDA, List of Drug Master Files
View profile
07

Veranova Lp

United States
Makes the API
Credentials confirmed against the regulator files on 25 July 2026

Holds one active US DMF for codeine, filing since 2007.

US DMF
1 active
CEP
None on file
Last FDA inspection
Not established
GMP recognised in
Not established
How this listing is sourced FDA, List of Drug Master Files
View profile
09

S,A.L.A.R.S

Italy
Makes the API
Credentials confirmed against the regulator files on 25 July 2026

US DMF
None on file
CEP
None on file
Last FDA inspection
Not established
GMP recognised in
Not established
How this listing is sourced EDQM certificate database
View profile
10

TV. Pharm

Vietnam
Makes the API

Registered with DAV (Vietnam) for codeine.

US DMF
None on file
CEP
None on file
Last FDA inspection
Not established
GMP recognised in
Not established
How this listing is sourced Regulator filings, warehouse snapshot 9 July 2026
View profile
11

Vacopharm Pharmaceutical Joint Stock

Vietnam
Makes the APIFinished dose

Registered with DAV (Vietnam) for codeine. Its GMP is recognised in 1 market.

US DMF
None on file
CEP
None on file
Last FDA inspection
Not established
GMP recognised in
1 markets
How this listing is sourced Regulator filings, warehouse snapshot 9 July 2026
View profile
12

Imexpharm

Vietnam
Makes the API

Registered with DAV (Vietnam) for codeine. Its GMP is recognised in 1 market.

US DMF
None on file
CEP
None on file
Last FDA inspection
Not established
GMP recognised in
1 markets
How this listing is sourced Regulator filings, warehouse snapshot 9 July 2026
View profile
13

Công ty Cổ phần Nam Dược

Vietnam
Makes the APIFinished dose

Registered with DAV (Vietnam) for codeine. Its GMP is recognised in 1 market.

US DMF
None on file
CEP
None on file
Last FDA inspection
Not established
GMP recognised in
1 markets
How this listing is sourced Regulator filings, warehouse snapshot 9 July 2026
View profile
14

Công ty cổ phần Dược phẩm Cửu Long

Vietnam
Makes the APIFinished dose

Registered with DAV (Vietnam) for codeine. Its GMP is recognised in 1 market.

US DMF
None on file
CEP
None on file
Last FDA inspection
Not established
GMP recognised in
1 markets
How this listing is sourced Regulator filings, warehouse snapshot 9 July 2026
View profile

Registered with DAV (Vietnam) for codeine. Its GMP is recognised in 1 market.

US DMF
None on file
CEP
None on file
Last FDA inspection
Not established
GMP recognised in
1 markets
How this listing is sourced Regulator filings, warehouse snapshot 9 July 2026
View profile
16

Pharbaco

Vietnam
Makes the APIFinished dose

Registered with DAV (Vietnam) for codeine. Its GMP is recognised in 1 market.

US DMF
None on file
CEP
None on file
Last FDA inspection
Not established
GMP recognised in
1 markets
How this listing is sourced Regulator filings, warehouse snapshot 9 July 2026
View profile
17

Mekophar Chemical Pharmaceutical

Vietnam
Makes the APIFinished dose

Registered with DAV (Vietnam) for codeine. Its GMP is recognised in 2 markets.

US DMF
None on file
CEP
None on file
Last FDA inspection
Not established
GMP recognised in
2 markets
How this listing is sourced Regulator filings, warehouse snapshot 9 July 2026
View profile
18

Công Ty Cổ Phần Dược Phẩm Tv.Pharm

Vietnam
Makes the APIFinished dose

Registered with DAV (Vietnam) for codeine. Its GMP is recognised in 1 market.

US DMF
None on file
CEP
None on file
Last FDA inspection
Not established
GMP recognised in
1 markets
How this listing is sourced Regulator filings, warehouse snapshot 9 July 2026
View profile
19

Registered with DAV (Vietnam) for codeine. Its GMP is recognised in 1 market.

US DMF
None on file
CEP
None on file
Last FDA inspection
Not established
GMP recognised in
1 markets
How this listing is sourced Regulator filings, warehouse snapshot 9 July 2026
View profile
20

SaVipharm J.S.C

Vietnam
Makes the API

Registered with DAV (Vietnam) for codeine. Its GMP is recognised in 1 market.

US DMF
None on file
CEP
None on file
Last FDA inspection
Not established
GMP recognised in
1 markets
How this listing is sourced Regulator filings, warehouse snapshot 9 July 2026
View profile

Contract manufacturers (3)

Contract manufacturers make to order rather than holding their own filing for this molecule.

How this list is built

The order is set by active filings weighted by regulator, inspection outcomes and their recency, breadth of GMP recognition, and evidence of real exports, less any open risk flags. Every factor appears on the card it produced. Read the full method.

Active US DMFs
FDA, List of Drug Master Files
Valid CEPs
EDQM certificate database
Inspection outcomes
FDA inspection classifications
GMP certificates
EudraGMDP and national regulators

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