PharmaDB
Use case · Pricing & Cost Benchmarks · Multi-Strength Pricing Strategy v.04.2026 · refreshed weekly
Use cases Pricing & Cost Benchmarks Multi-Strength Pricing Strategy
Pricing & Cost Benchmarks Buyer view Molecule · lenalidomide Data · molecule FDF price aggregates Live

Multi-Strength Pricing Strategy

Compare clearance prices across strengths and pack sizes for the same molecule. The empirical strength-cascade map for pricing architecture and arbitrage prevention.

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Example output · lenalidomide FDF, 2024 · 7 strength/pack combos · capsule form · 156 shipments aggregated
$19.87 USD per pack (median across strengths) · median · the bid line
n=156 shipments across 7 strength/pack combos · trade warehouse Indicative

Lenalidomide clears the FDF market in at least seven distinct strength/pack combinations in 2024. The 25mg / 21-cap pack clears at $33.67 median, while the same 25mg in a 30-cap pack clears at $19.87, with a duplicate cluster at $20.86. The 15mg / 21-cap pack sits at $21.99, and 10mg sits in the $15.22 to $20.35 band depending on pack count. The per-mg economics: 25mg / 21-cap is $0.064/mg, 10mg / 30-cap is $0.051/mg. The 10mg pack is structurally cheaper per mg, which means a buyer can arbitrage between strengths if the prescriber substitutes downward. The cascade needs an explicit pricing rule, not a per-pack quote.

p25 · aggressive entry
$15.22
deals get done
median · the bid line
$19.87
where the market clears
p75 · premium
$33.67
likely loses
Distribution · 10 price buckets
$14
$16
$18
$20
$22
$24
$26
$28
$30
$33
Strength/pack combos
7
Highest per-pack (25mg/21)
$33.67
Lowest per-pack (10mg/30)
$15.22
Per-mg range
$0.05-$0.06
30 seconds

How it works

molecule losartan origin IN destination BR
01

Pick a molecule.

Type the molecule INN. The AI agent pulls every form-strength-pack combination with declared clearance shipments.

0 HHI 0.42 1
computed · pre-joined · anonymised
02

The AI agent builds the cascade.

Per-pack median, per-mg of active ingredient, and the implied price ratio between adjacent strengths. Pricing anomalies (where 2x strength costs less than 2x the half) are flagged.

brief · cited
Lane concentration · structurally concentrated
HHI0.42
Top-3 share71%
Actionqualify second source
03

Save the cascade brief.

Citation-anchored brief: the full strength/pack table, the per-mg comparison, and a chip on any anomalies that suggest substitution risk or revenue leakage.

Why a pricing team runs it

Cascade pricing, with the substitution risk surfaced.

Empirical, per form-strength-pack.

Each combination is its own market clearance band. Aggregating them obscures the cascade; surfacing them individually reveals where the strength uplift is or is not priced.

Per-mg comparison.

USD per mg of active ingredient is the comparable unit across strengths. Linear cascade means uniform per-mg; non-linear surfaces as a pricing anomaly the user can act on.

Substitution risk flagged.

When the 2x-strength pack is below 2x the half-strength pack price per pack, prescribers can substitute upward at the buyer's expense. The brief flags these anomalies so the cascade can be corrected.

Refreshes weekly.

FDF aggregates refresh weekly. The cascade reruns on every refresh; the brief carries the exact computation timestamp.

What a real chat looks like

Type a molecule. The AI agent returns the cascade.

A real chat thread in PharmaDB. Type a question, the AI agent runs the tools, the answer lands as a saveable note.

Strength cascade · lenalidomide FDF
chat · saved 2 min ago
You
For lenalidomide, compare the FDF median pack price across all available strengths and pack sizes.
F
Running tool pharmagraph_query
molecule_fdf_prices · lenalidomide · 2024 · 7 strength/pack combos
F
Lenalidomide cascade across seven combos in 2024: 25mg/21-cap at $33.67 (highest per-pack), 15mg/21-cap at $21.99, and 10mg/30-cap at $15.22 (lowest per-pack). The per-mg economics: 25mg/21-cap = $0.064/mg, 10mg/30-cap = $0.051/mg. The 25mg pack is 26% more expensive per mg, which is consistent with strength-uplift pricing on oncology generics. No anomaly flagged; the cascade is internally consistent. Recommend holding the per-pack quote sheet at the warehouse medians and reviewing on the next refresh.
25mg / 21-cap
$33.67
15mg / 21-cap
$21.99
10mg / 30-cap
$15.22
Per-mg range
$0.051-$0.064
Cited molecule_fdf_prices 7 combos · 156 shipments molecule_catalog INN matched molecule_api_prices for embedded cost reference
Ask a follow-up... ⌘ ↵
Time-to-answer

Manual workflow vs. PharmaDB.

Manual workflow
Excel · email · syndicated reports
  1. 01 Pull FDF clearance for every strength/pack 3-4 hr
  2. 02 Compute per-pack medians 1-2 hr
  3. 03 Normalise to per-mg active 1-2 hr
  4. 04 Compute strength ratios 1 hr
  5. 05 Flag pricing anomalies 2 hr
Total cycle time 1 day per molecule
PharmaDB
The AI agent · one query · cited
One query.
Pre-joined warehouse. The FDF percentile aggregate is keyed on form-strength-pack; the per-mg normalisation is computed inline. The AI agent returns the cascade with the anomaly chip.
Total cycle time Under a minute
Run it across your portfolio

Where the strength cascade sits, per molecule.

Twelve form-strength-pack combinations · 2024 FDF median · per-pack USD · capsule and tablet.

Apixaban 2.5mg · 30 tab
$3.75
↑ 2%
Apixaban 5mg · 30 tab
$4.27
↑ 5%
Tofacitinib 5mg · 60 tab
$9.37
↑ 1%
Imatinib 400mg · 30 tab
$9.38
↓ 3%
Lenalidomide 10mg · 30 cap
$15.22
↓ 5%
Lenalidomide 25mg · 30 cap
$19.87
↓ 5%
Lenalidomide 15mg · 21 cap
$21.99
↓ 3%
Palbociclib 125mg · 21 cap
$21.54
↑ 0%
Enzalutamide 40mg · 28 cap
$26.54
↑ 2%
Lenalidomide 25mg · 21 cap
$33.67
↓ 4%
Olaparib 150mg · 30 tab
$43.96
↑ 1%
Ibrutinib 140mg · 30 cap
$45.48
↓ 2%
IQR (p25–p75) Median USD per pack ↓ YoY price drop · margin pressure · ↑ YoY price rise · tighter market

The strength cascade is the pricing architecture lens. PharmaDB pulls every form-strength-pack combination from molecule_fdf_prices, normalises to per-mg of active ingredient, and surfaces anomalies in the cascade. Refresh cadence is weekly.

FAQ

Frequently asked

What is a strength cascade?+

The set of all strengths and pack sizes in which a molecule is sold. Pricing across the cascade should be internally consistent: 2x strength priced near 2x the half-strength pack, larger packs priced with the typical bulk discount. Deviation from consistency is a pricing anomaly worth investigating.

Why per-mg of active ingredient?+

The fairest comparison across strengths. A 25mg pack and a 10mg pack are not the same product; the per-mg comparison normalises across both. Non-linear per-mg pricing means the strengths are priced as distinct SKUs, not as a cascade.

What if the same combination has two clearance prices?+

Common. Branded equivalent vs generic, parallel-import vs domestic, two regional anchor prices. PharmaDB surfaces both as separate rows. The brief flags the bimodal distribution and notes the spread.

Does this account for tablet vs capsule differences?+

Yes. The form field separates tablets from capsules; cascades are computed within form first. Cross-form comparison is reported separately for the user to interpret (different bioavailability, different manufacturing economics).

What is the substitution risk?+

When the per-mg price is lower on the lower-strength pack, prescribers can substitute (two 10mg in place of one 25mg) and capture savings at the buyer's cost. PharmaDB flags this anomaly explicitly so the cascade can be repriced.

How fresh is the data?+

FDF aggregates refresh weekly. The cascade reruns on every refresh; the catalog row carries the exact timestamp.

Run your question.

Bring the molecule, the lane, or the supplier you're sourcing this week. The AI agent runs it on PharmaDB in 30 minutes. You keep the brief.

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